Search for tag: "clinical trials"

ScHARR Mini Master Class in Health Research #29 Efficient adaptive trial designs: what are they, what to consider when using them, and how to improve their uptake to transform patient care - Dr Munya…

AbstractResearch shows that participants in clinical trials rarely reflect the populations that could benefit from the treatments being tested, for example, COVID-19 disproportionately affected older…

Short talks on how University of Sheffield researchers and RSEs, and collaborators worldwide, are using REDCap and other platforms to handle clinical research data. The clinical research we will…

AbstractClinical research is expensive. For this reason there is a design to undertake studies as efficiently as possible whilst maintaining scientific standards. This presentation will first define…

The ABC of RCTs This talk will emphasise the importance of randomised clinical trials in evaluating alternative treatments or interventions. The rationale for, and methods of, randomising patients…

This video is a summary of the results of the Big CACTUS study. For more information on this study, please visit: https://www.sheffield.ac.uk/scharr/sections/dts/ctru/bigcactus

This video looks at randomization when the patients are grouped into clusters. Since the clusters tend to be relatively few, getting balance is generally more important than with simple randomization.

This video looks at a different form of randomization, minimization. This method can be more efficient than stratification at ensuring balance in important predictive characteristics, but is not true…

This video introduces the concept of randomization of treatments to patients using playing cards. It describes simple randomisation, which is the purest form of randomization

This video introduces the three main concepts in Randomized Trials, the ABC: Allocation at random, Blindness and Control

This video looks two methods of trying to get a better balance between two groups namely blocked randomization and stratified randomization. Blocked randomisation tries to ensure that approximately…