ScHARR Mini Master Class in Health Research 9 - Professor Steven Julious
From Andy Tattersall
Clinical research is expensive. For this reason there is a design to undertake studies as efficiently as possible whilst maintaining scientific standards. This presentation will first define what efficient study designs are. They are in fact a broad range of trial enhancements and include methods of data collection through to novel study design called adaptive designs.
The talk has a practical focus. It will explain how efficient designs can be utilised in clinical research through a series of real world examples which will highlight both their advantages and challenges
Steven graduated with a BSc (Hons) in Mathematics, Statistics and Operational Research (MSOR) from the University of Manchester Institute of Science and Technology (UMIST) and an MSc in Biometry from the University of Reading. He gained his PhD from University College London, which Steven did part-time while working in the industry, and investigated the issue of designing clinical trials when you have imprecise estimates to base calculations on. Statistically, Steven has an interest in all aspects of clinical trials from molecule through to the marketplace. His main research focus is clinical trial design and the development of applied methods related to clinical trials. Steven has a particular interest around adaptive designs and the implementation of adaptive designs into practice.
The methodologies around sample size estimation are a particular interest and as well as a book he has developed a mobile app for the calculations called SampSize.
Steven has also an interest in asthma epidemiology and is the Chief Investigator of the PLEASANT trial: Preventing and Lessening Exacerbations of Asthma in School-age children Associated with a New Term.