Improving the current preclinical assessment of new interventions is fundamental to optimise the development of new treatments!

Motivation:

The goal of application 3 is to generate a computational and experimental framework to evaluate the effect of novel interventions against diseases of the musculoskeletal system in a preclinical setting, using in vitro analyses, in vivo longitudinal experiments with a small number of mice and in silico approaches including finite element models, bone remodelling algorithms and agent based models at the molecular level.