This video is intended as an informative revision guide video about the neural circuit involved in the motor loop to initiate movement and how this circuit is interfered with by Huntington’s disease.

Aimed at L1 Biomedical Science students, our group focused on thos topic as we collectively found it a difficult concept to grasp in Level 1 - hopefully this video will fill that gap.

The video begins with an outline of the topics covered, moving on to:

• the nuclei involved in the motor loop, showing their relation in the coronal slice of the brain.
• the pathway of the motor loop with the aid of animations overlaid on the labelled coronal slice.
• Finally, giving a brief introduction to general aspects of Huntington’s disease, followed by how it causes hyperkinesia and akinesia.
  

Furthermore, through this video we will highlight how to integrate content from multiple subjects, a technique examined in synoptic questions. Specifically, we will combine Cell and Molecular (showing codon repeats of CAG leads increased polyglutamine tract), Neuroanatomy (showing different nuclei locations in the brain) and Neuroscience (showing the neural circuit pathway).

Video made by: Jason Perera, Thomas Allen, Ryan Lewis, Samuel Boldan